Alzheimer's»

Works cited

Every fact, with a source.

This site uses peer-reviewed research articles plus the Alzheimer's Association, the National Institute on Aging, the CDC, the WHO and the FDA.

See the research articles
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01 / Research journal articles

Peer-reviewed research

  1. Journal articleLee JH, Yu WH, Kumar A, et al. (2010). Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell 141(7):1146-1158. https://www.cell.com/cell/fulltext/S0092-8674(10)00544-1
  2. Journal articleLee JH, Yang DS, Goulbourne CN, et al., Nixon RA (2022). Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques. Nature Neuroscience 25:688-701. https://pmc.ncbi.nlm.nih.gov/articles/PMC9174056
  3. Journal articleNixon RA, Rubinsztein DC (2024). Mechanisms of autophagy-lysosome dysfunction in neurodegenerative diseases. Nature Reviews Molecular Cell Biology 25:926-946. https://pmc.ncbi.nlm.nih.gov/articles/PMC12239022/

02 / All other sources

Websites and reports

  1. Alberts et al. Molecular Biology of the Cell, Lysosomes (NCBI Bookshelf). https://www.ncbi.nlm.nih.gov/books/NBK26882/
  2. Alzheimer Europe. EVOKE and EVOKE+ trials show no effect of oral semaglutide (2025). https://www.alzheimer-europe.org/news/results-evoke-and-evoke-trials-show-no-effect-oral-semaglutide-ad-progression
  3. Alzheimer's Association. 2026 Alzheimer's Disease Facts and Figures (Alzheimer's & Dementia, 2026). https://pmc.ncbi.nlm.nih.gov/articles/PMC13098189/
  4. Alzheimer's Association. Alzheimer's Facts and Figures. https://www.alz.org/alzheimers-dementia/facts-figures
  5. Alzheimer's Association. Causes and Risk Factors for Alzheimer's Disease. https://www.alz.org/alzheimers-dementia/what-is-alzheimers/causes-and-risk-factors
  6. Alzheimer's Association. Glen Campbell Sings to Congress (2012). https://www.alz.org/blog/2012/glen_campbell_sings_to_congress_keeps_alzheimer_s
  7. Alzheimer's Association. Inside the Brain: A Tour of How the Mind Works, Part 2. https://www.alz.org/alzheimers-dementia/what-is-alzheimers/brain-tour-part-2
  8. Alzheimer's Association. Is Alzheimer's Genetic? https://www.alz.org/alzheimers-dementia/what-is-alzheimers/causes-and-risk-factors/genetics
  9. Alzheimer's Association. Medications for Memory, Cognition and Dementia-Related Behaviors. https://www.alz.org/alzheimers-dementia/treatments/medications-for-memory
  10. Alzheimer's Association. Stages of Alzheimer's. https://www.alz.org/alzheimers-dementia/stages
  11. Alzheimer's Association. What Is Alzheimer's Disease? https://www.alz.org/alzheimers-dementia/what-is-alzheimers
  12. CDC National Center for Health Statistics. FastStats: Alzheimer's Disease. https://www.cdc.gov/nchs/fastats/alzheimers.htm
  13. Cleveland Clinic. Alzheimer's Disease. https://my.clevelandclinic.org/health/diseases/9164-alzheimers-disease
  14. ClinicalTrials.gov. TRONTIER 1 phase 3 trial of trontinemab (NCT07169578). https://clinicaltrials.gov/study/NCT07169578
  15. Eli Lilly. Kisunla (donanemab) approved by FDA (2024). https://investor.lilly.com/news-releases/news-release-details/lillys-kisunlatm-donanemab-azbt-approved-fda-treatment-early
  16. Fox News. Glen Campbell's wife says singer has lost ability to speak (2016). https://www.foxnews.com/entertainment/glen-campbells-wife-says-singer-has-lost-ability-to-speak
  17. Glen Campbell. I'm Not Gonna Miss You, official music video (GlenCampbellVEVO, 2014). https://www.youtube.com/watch?v=U8TsAh-zYFI
  18. Key brain cell interactions in Alzheimer's (PMC9745159). https://pmc.ncbi.nlm.nih.gov/articles/PMC9745159/
  19. KMUW. Glen Campbell's Wife Reflects On The Country Legend's Battle With Alzheimer's (2017). https://www.kmuw.org/music/2017-11-01/glen-campbells-wife-reflects-on-the-country-legends-battle-with-alzheimers
  20. KQED. New Documentary Chronicles Glen Campbell's Farewell (2014). https://www.kqed.org/arts/10145308/new-documentary-chronicles-glen-campbells-farewell
  21. Kupffer Cells in Health and Disease (PMC7121975). https://pmc.ncbi.nlm.nih.gov/articles/PMC7121975/
  22. Lysosome remodeling review (PMC9189017). https://pmc.ncbi.nlm.nih.gov/articles/PMC9189017/
  23. Lysoway Therapeutics. Phase I dosing of LW-1017 (2026). https://www.lysoway.com/companynews/lysoway-therapeutics-announces-phase-i-dosing-of-lw-1017-the-first-trpml1-agonist-to-enter-clinical-development/
  24. Medscape. Trontinemab rapidly clears amyloid with less ARIA (2025). https://www.medscape.com/viewarticle/trontinemab-rapidly-clears-amyloid-less-aria-2025a1000xzj
  25. Mitochondria and mitophagy in Alzheimer's review (PMC6880761). https://pmc.ncbi.nlm.nih.gov/articles/PMC6880761/
  26. Mitophagy in Alzheimer's disease review (PMC7017092). https://pmc.ncbi.nlm.nih.gov/articles/PMC7017092/
  27. National Institute on Aging. Alzheimer's Disease Fact Sheet. https://www.nia.nih.gov/health/alzheimers-and-dementia/alzheimers-disease-fact-sheet
  28. National Institute on Aging. Alzheimer's Disease in People with Down Syndrome. https://www.nia.nih.gov/health/alzheimers-causes-and-risk-factors/alzheimers-disease-people-down-syndrome
  29. National Institute on Aging. Caring for a Person with Alzheimer's Disease (booklet). https://www.govinfo.gov/content/pkg/GOVPUB-HE20_3850-PURL-LPS33434/pdf/GOVPUB-HE20_3850-PURL-LPS33434.pdf
  30. National Institute on Aging. Staying Physically Active with Alzheimer's. https://www.nia.nih.gov/health/exercise-and-physical-activity/staying-physically-active-alzheimers
  31. National Institute on Aging. What Happens to the Brain in Alzheimer's Disease? https://www.nia.nih.gov/health/alzheimers-causes-and-risk-factors/what-happens-brain-alzheimers-disease
  32. NeurologyLive. Lecanemab Clarity AD results. https://www.neurologylive.com/view/alzheimer-disease-lecanemab-reduction-cdr-sum-boxes-clarity-ad
  33. Neuronal Lysosomes review (PMC6170731). https://pmc.ncbi.nlm.nih.gov/articles/PMC6170731/
  34. Neuropathology of Alzheimer's disease update (PMC10209886). https://pmc.ncbi.nlm.nih.gov/articles/PMC10209886/
  35. OpenStax Anatomy and Physiology 2e, 1.5 Homeostasis. https://openstax.org/books/anatomy-and-physiology-2e/pages/1-5-homeostasis
  36. OpenStax Biology 2e, 4.3 Eukaryotic Cells. https://openstax.org/books/biology-2e/pages/4-3-eukaryotic-cells
  37. pharmaphorum. Major trial of Roche Alzheimer's drug kicks off (2026). https://pharmaphorum.com/news/major-trial-roche-alzheimers-drug-kicks-europe
  38. Roche. Trontinemab phase Ib/IIa data (July 28, 2025). https://www.roche.com/media/releases/med-cor-2025-07-28
  39. The Hollywood Reporter. 'Glen Campbell: I'll Be Me' review (2014). https://www.hollywoodreporter.com/movies/movie-reviews/glen-campbell-ill-be-me-743438/
  40. U.S. FDA. FDA Approves First Home Starting Dose for Alzheimer's Disease Treatment (2026). https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-first-home-starting-dose-alzheimers-disease-treatment
  41. U.S. FDA. FDA Clears First Blood Test Used in Diagnosing Alzheimer's Disease (2025). https://www.fda.gov/news-events/press-announcements/fda-clears-first-blood-test-used-diagnosing-alzheimers-disease
  42. U.S. FDA. FDA Converts Novel Alzheimer's Disease Treatment to Traditional Approval (2023). https://www.fda.gov/news-events/press-announcements/fda-converts-novel-alzheimers-disease-treatment-traditional-approval
  43. U.S. FDA. Leqembi prescribing information (2026). https://www.accessdata.fda.gov/drugs/label/2026/761375s001lbl.pdf
  44. UCLA Health. What is the cause of death in Alzheimer's disease? https://www.uclahealth.org/news/article/ask-the-doctors-what-is-the-cause-of-death-in-alzheimers-disease
  45. Variety. Film Review: 'Glen Campbell: I'll Be Me' (2014). https://variety.com/2014/film/festivals/film-review-glen-campbell-ill-be-me-1201322175/
  46. WAMC / NPR. Glen Campbell, Country Music Legend, Is Dead At 81 (2017). https://www.wamc.org/2017-08-08/glen-campbell-country-music-legend-is-dead-at-81
  47. Wikipedia. Glen Campbell (used to cross-check dates). https://en.wikipedia.org/wiki/Glen_Campbell
  48. Wikipedia. I'm Not Gonna Miss You (used to cross-check awards). https://en.wikipedia.org/wiki/I%27m_Not_Gonna_Miss_You
  49. World Health Organization. Dementia fact sheet. https://www.who.int/news-room/fact-sheets/detail/dementia
Healthy neuron vs a neuron with plaques and tangles.
Healthy neuron vs a neuron with plaques and tangles.
Image: BruceBlaus (Blausen Medical), CC BY 3.0, Wikimedia Commons
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